HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(8-Hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)pyridine-2-carbonitrile → 5-(1-Hydroxy-4-oxocyclohexyl)pyridine-2-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(8-Hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)pyridine-2-carbonitrile | HCID 66787096 | — |
| Reactant | 4-(1-Hydroxy-4-oxocyclohexyl)benzonitrile | HCID 66787229 | — |
| Product | 5-(1-Hydroxy-4-oxocyclohexyl)pyridine-2-carbonitrile | HCID 66787388 | — |
Reaction Steps
The title compound was synthesized from 5-(8-hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)pyridine-2-carbonitrile using the same typical deprotection procedure as for 4-(1-hydroxy-4-oxocyclohexyl)benzonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729063B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-0377984307a64ac0bc8958d23eb2bb4e |
| Source note | uspto-grants-2014_05 |