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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1025945Generated: October 26, 2026

Bromomethylcyclopropane → (6-Chloro-4-iodo-5-cyclopropylmethoxy-pyridin-2-yl)-methanol

https://huagongshe.com/reaction/1025945

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromomethylcyclopropaneHCID 81503—
Reactant2-Chloro-6-(hydroxymethyl)-4-iodo-3-pyridinolHCID 10684568—
Product(6-Chloro-4-iodo-5-cyclopropylmethoxy-pyridin-2-yl)-methanolHCID 86663132—

Reaction Steps

The title compound was synthesized in analogy to Example A, using 6-chloro-5-hydroxy-4-iodo-2-pyridinemethanol and cyclopropylmethyl bromide as starting materials; LC-MS (UV peak area/ESI) 95.8%, 339.9584 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729105B2
Source datasetuspto-grants-2014_05
ORD IDord-6d45c1069b1e48728ad3d12f84ef2534
Source noteuspto-grants-2014_05