HuagongsheHuagongshe Chemistry Print Report · For research reference only
[(1-propyl-1H-pyrazol-3-yl)methyl]amine → 4-(4-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (1-propyl-1H-pyrazol-3-ylmethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [(1-propyl-1H-pyrazol-3-yl)methyl]amine | HCID 19576818 | — |
| Reactant | HCID 66687043 | HCID 66687043 | — |
| Product | 4-(4-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (1-propyl-1H-pyrazol-3-ylmethyl)-amide | HCID 56929660 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 4-(4-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (example D) and 1-propyl-1H-pyrazole-3-methanamine (CAS Registry No. 1006333-47-6) as starting materials; LC-MS (UV peak area/ESI) 100%, 453.1306 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729105B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-0e76303ad6db4eed8920173751370725 |
| Source note | uspto-grants-2014_05 |