HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Isopropylthiazol-4-yl)methanamine → 4-(4-Chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (2-isopropyl-thiazol-4-ylmethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Isopropylthiazol-4-yl)methanamine | HCID 16427107 | — |
| Reactant | HCID 66687043 | HCID 66687043 | — |
| Product | 4-(4-Chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (2-isopropyl-thiazol-4-ylmethyl)-amide | HCID 56929756 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 4-(4-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (example D) and 2-(1-methylethyl)-4-thiazole-methanamine, as starting materials; LC-MS (UV peak area/ESI) 80%, 470.902 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729105B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-918f49d46ed14cc5881e0dec1d9ddd2a |
| Source note | uspto-grants-2014_05 |