HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Methoxyisoxazol-5-yl)methanamine hydrochloride → 5-(4-chlorophenyl)-N-((3-methoxyisoxazol-5-yl)methyl)-6-(2,2,2-trifluoroethoxy)pyridazine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Methoxyisoxazol-5-yl)methanamine hydrochloride | HCID 21292276 | — |
| Reactant | HCID 66678582 | HCID 66678582 | — |
| Product | 5-(4-chlorophenyl)-N-((3-methoxyisoxazol-5-yl)methyl)-6-(2,2,2-trifluoroethoxy)pyridazine-3-carboxamide | HCID 66678623 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridazine-3-carboxylic acid (example M) and 3-methoxy-5-isoxazole-methanamine hydrochloride as starting materials, 443.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729105B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-43d09a068ac6439882571f2845ea20d2 |
| Source note | uspto-grants-2014_05 |