HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(1-Methylethyl)-3-isoxazolemethanamine → 5-(4-chlorophenyl)-6-(cyclopropylmethoxy)-N-((5-isopropylisoxazol-3-yl)methyl)nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(1-Methylethyl)-3-isoxazolemethanamine | HCID 28065151 | — |
| Reactant | 5-(4-Chlorophenyl)-6-(cyclopropylmethoxy)nicotinic acid | HCID 66687482 | — |
| Product | 5-(4-chlorophenyl)-6-(cyclopropylmethoxy)-N-((5-isopropylisoxazol-3-yl)methyl)nicotinamide | HCID 56928592 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-(4-chloro-phenyl)-6-cyclopropylmethoxy-nicotinic acid (CAS Registry No. 1018782-76-7) and 5-(1-methylethyl)-3-isoxazolemethanamine (CAS Registry No. 154016-49-6) as starting materials, 426.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729105B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-ff62c4c1e4a248e0b5afd2d34055dbec |
| Source note | uspto-grants-2014_05 |