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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1026044Generated: October 30, 2026

HCID 66678582, compound → 5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridazine-3-carboxylic acid (3-trifluoromethyl-[1,2,4]oxadiazol-5-ylmethyl)-amide

https://huagongshe.com/reaction/1026044

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66678582HCID 66678582—
Reactant[3-(Trifluoromethyl)-1,2,4-oxadiazol-5-yl]methanamine hydrochlorideHCID 66687518—
Product5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridazine-3-carboxylic acid (3-trifluoromethyl-[1,2,4]oxadiazol-5-ylmethyl)-amideHCID 56928797—

Reaction Steps

The title compound was synthesized in analogy to Example 41, using 5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridazine-3-carboxylic acid (example M) and C-(3-trifluoromethyl-[1,2,4]oxadiazol-5-yl)-methylamine hydrochloride (CAS registry No. 944905-93-5; example AK) as starting materials; LC-MS (UV peak area/ESI) 100.0%, 482.0 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729105B2
Source datasetuspto-grants-2014_05
ORD IDord-754b0390855c4b70943dba310be10fe5
Source noteuspto-grants-2014_05