HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxy-5-isoxazolemethanamine → 4-(3,4-dimethylphenyl)-N-((3-methoxyisoxazol-5-yl)methyl)-5-(2,2,2-trifluoroethoxy)picolinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxy-5-isoxazolemethanamine | HCID 2763227 | — |
| Reactant | 4-(3,4-Dimethylphenyl)-5-(2,2,2-trifluoroethoxy)picolinic acid | HCID 66678795 | — |
| Product | 4-(3,4-dimethylphenyl)-N-((3-methoxyisoxazol-5-yl)methyl)-5-(2,2,2-trifluoroethoxy)picolinamide | HCID 56929188 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1 using 4-(3,4-dimethylphenyl)-5-(2,2,2-trifluoroethoxy)picolinic acid (example BO) and 3-methoxy-5-isoxazolemethanamine (CAN 2763-94-2) as starting materials; LC-MS (UV peak area/ESI) 100%, 436.1476 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729105B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-168ccd71150b4029806930bf6ee158b9 |
| Source note | uspto-grants-2014_05 |