Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(3-Methyl-1,2,4-oxadiazol-5-yl)methanamine → 5-(4-chlorophenyl)-N-((3-methyl-1,2,4-oxadiazol-5-yl)methyl)-6-(2,2,2-trifluoroethoxy)nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (3-Methyl-1,2,4-oxadiazol-5-yl)methanamine | HCID 10844548 | — |
| 반응물 | 5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid | HCID 66686971 | — |
| 생성물 | 5-(4-chlorophenyl)-N-((3-methyl-1,2,4-oxadiazol-5-yl)methyl)-6-(2,2,2-trifluoroethoxy)nicotinamide | HCID 56929463 | — |
반응 단계
The title compound was synthesized in analogy to Example 1 using 5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (CAN 1018782-82-5) and 3-methyl-1,2,4-oxadiazole-5-methanamine (CAN 90928-92-0) as starting materials; LC-MS (UV peak area/ESI) 100%, 425.0644 (M−H)−.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08729105B2 |
| 출처 데이터셋 | uspto-grants-2014_05 |
| ORD ID | ord-12a3639978aa403ebe0c23284ddee5be |
| 출처 메모 | uspto-grants-2014_05 |