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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1026083Generated: October 31, 2026

(3-(Trifluoromethyl)-1,2,4-oxadiazol-5-YL)methanamine → HCID 56929464, compound

https://huagongshe.com/reaction/1026083

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-(Trifluoromethyl)-1,2,4-oxadiazol-5-YL)methanamineHCID 55263061—
Reactant6-(Cyclobutyloxy)-5-(3,4-difluorophenyl)-3-pyridinecarboxylic acidHCID 66678844—
ProductHCID 56929464HCID 56929464—

Reaction Steps

The title compound was synthesized in analogy to Example 1 using 6-cyclobutoxy-5-(3,4-difluorophenyl)nicotinic acid (example BZ) and 3-trifluoromethyl-[1,2,4]oxadiazol-5-methanamine (example AK) as starting materials; LC-MS (UV peak area/ESI) 98.0%, 455.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729105B2
Source datasetuspto-grants-2014_05
ORD IDord-467decc838a44142a7b941f2edbf809d
Source noteuspto-grants-2014_05