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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1026093Generated: October 31, 2026

2-Pyridinemethanamine → 5-(4-chlorophenyl)-6-cyclobutoxy-N-(pyridin-2-ylmethyl)nicotinamide

https://huagongshe.com/reaction/1026093

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-PyridinemethanamineHCID 19509—
Reactant5-(4-Chlorophenyl)-6-cyclobutoxy-nicotinic acidHCID 66678618—
Product5-(4-chlorophenyl)-6-cyclobutoxy-N-(pyridin-2-ylmethyl)nicotinamideHCID 56929564—

Reaction Steps

The title compound was synthesized in analogy to Example 1 using 5-(4-chlorophenyl)-6-cyclobutoxy-nicotinic acid (example CA) and 2-pyridinemethanamine (CAN 3731-51-9) as starting materials; LC-MS (UV peak area/ESI) 99.0%, 394.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729105B2
Source datasetuspto-grants-2014_05
ORD IDord-119bbd7b14bd41e6b6206123b73e0dd1
Source noteuspto-grants-2014_05