Methyl iodide → HCID 67777940, compound

HRID 1026225Notes

Reaction equation

[C:1]([O:5][C:6]([NH:8][C@@H:9]([CH3:21])[CH2:10][O:11][C:12]1[CH:16]=[C:15]([C:17]([O:19][CH3:20])=[O:18])[NH:14][N:13]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].I[CH3:23]>>[C:1]([O:5][C:6]([NH:8][C@@H:9]([CH3:21])[CH2:10][O:11][C:12]1[CH:16]=[C:15]([C:17]([O:19][CH3:20])=[O:18])[N:14]([CH3:23])[N:13]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 67778799HCID 67778799, compound

Product 1

HCID 67777940HCID 67777940, compound

Procedure

Using methyl 3-({(2S)-2-[(tert-butoxycarbonyl)amino]propyl}oxy)-1H-pyrazole-5-carboxylate and iodomethane, and in the same manner as in Example 8, step B, the title compound was obtained.

Sources & evidence

ORD record: ord-8df9e5c890a8419b923990c1fea0c386
Source dataset: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08729102B2

Reaction notes

Loading…