5-(Benzyloxy)-2-chloropyridine → HCID 67778348, compound

HRID 1026233Notes

Reaction equation

HRID 1026233 reaction equation
[CH:1]1([CH2:4][O:5][C:6]2[CH:14]=[C:13]3[C:9]([CH:10]=[N:11][NH:12]3)=[CH:8][CH:7]=2)[CH2:3][CH2:2]1.[CH2:15]([O:22][C:23]1[CH:24]=[CH:25][C:26](Cl)=[N:27][CH:28]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH2:15]([O:22][C:23]1[CH:24]=[CH:25][C:26]([N:11]2[CH:10]=[C:9]3[C:13]([CH:14]=[C:6]([O:5][CH2:4][CH:1]4[CH2:2][CH2:3]4)[CH:7]=[CH:8]3)=[N:12]2)=[N:27][CH:28]=1)[C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 100137175-(Benzyloxy)-2-chloropyridineHCID 67778171HCID 67778171, compound

Product 1

HCID 67778348HCID 67778348, compound

Procedure

Using 6-(cyclopropylmethoxy)-1H-indazole and 5-(benzyloxy)-2-chloropyridine, and in the same manner as in Example 13, step B, the title compound was obtained.

Sources & evidence

ORD record
ord-5d74d122ba184bc2b3c2f85f7824c06f
Source dataset
uspto-grants-2014_05
Patent number
US08729102B2

Reaction notes

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