HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromoacetone → tert-butyl [(1S)-1-methyl-2-({6-[6-(2-oxopropoxy)-1,3-benzoxazol-2-yl]pyridin-3-yl}oxy)ethyl]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromoacetone | HCID 11715 | — |
| Reactant | tert-butyl [(1S)-2-{[6-(6-hydroxy-1,3-benzoxazol-2-yl)pyridin-3-yl]oxy}-1-methylethyl]carbamate | HCID 136372364 | — |
| Product | tert-butyl [(1S)-1-methyl-2-({6-[6-(2-oxopropoxy)-1,3-benzoxazol-2-yl]pyridin-3-yl}oxy)ethyl]carbamate | HCID 86666284 | — |
Reaction Steps
Using tert-butyl [(1S)-2-{[6-(6-hydroxy-1,3-benzoxazol-2-yl)pyridin-3-yl]oxy}-1-methylethyl]carbamate and 1-bromopropan-2-one, and in the same manner as in Example 2, step E, the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729102B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-868f10d4ace447838af56d13beac1c15 |
| Source note | uspto-grants-2014_05 |