HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethylhexyl 3-{[2-amino-5-(benzyloxy)phenyl]sulfanyl}propanoate → 2-ethylhexyl 3-{[2-{[(4-{[(2S)-2-(acetylamino)propyl]oxy}phenyl)carbonyl]amino}-5-(benzyloxy)phenyl]sulfanyl}propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethylhexyl 3-{[2-amino-5-(benzyloxy)phenyl]sulfanyl}propanoate | HCID 58047482 | — |
| Reactant | 4-{[(2S)-2-(acetylamino)propyl]oxy}benzoic acid | HCID 67778663 | — |
| Product | 2-ethylhexyl 3-{[2-{[(4-{[(2S)-2-(acetylamino)propyl]oxy}phenyl)carbonyl]amino}-5-(benzyloxy)phenyl]sulfanyl}propanoate | HCID 67778437 | 66.8% |
Reaction Steps
Using 2-ethylhexyl 3-{[2-amino-5-(benzyloxy)phenyl]sulfanyl}propanoate (1.00 g) and 4-{[(2S)-2-(acetylamino)propyl]oxy}benzoic acid (628 mg), and in the same manner as in Example 2, step C, the title compound (1.02 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729102B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-78e4939f7c5847b89028e65c6ced8169 |
| Source note | uspto-grants-2014_05 |