4-Aminobenzene-1,3-diol hydrochloride → HCID 86666288, compound

HRID 1026277Notes

Reaction equation

HRID 1026277 reaction equation
[CH2:1]([N:8]1[C:12]([C:13]([OH:15])=O)=[C:11]([CH3:16])[C:10]([O:17][CH2:18][C@@H:19]([NH:21][C:22]([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:23])[CH3:20])=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[NH2:30][C:31]1[CH:36]=[CH:35][C:34]([OH:37])=[CH:33][C:32]=1[OH:38]>>[CH2:1]([N:8]1[C:12]([C:13](=[O:15])[NH:30][C:31]2[CH:36]=[CH:35][C:34]([OH:37])=[CH:33][C:32]=2[OH:38])=[C:11]([CH3:16])[C:10]([O:17][CH2:18][C@@H:19]([NH:21][C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH3:20])=[N:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 134088224-Aminobenzene-1,3-diol hydrochlorideHCID 67778267HCID 67778267, compound

Product 1

HCID 86666288HCID 86666288, compound

Procedure

Using 1-benzyl-3-({(2S)-2-[(tert-butoxycarbonyl)amino]propyl}oxy)-4-methyl-1H-pyrazole-5-carboxylic acid and 4-aminobenzene-1,3-diol hydrochloride, and in the same manner as in Example 2, step C, the title compound was obtained.

Sources & evidence

ORD record
ord-f9ee98e410334d0d8b783f25c2a1ccb6
Source dataset
uspto-grants-2014_05
Patent number
US08729102B2

Reaction notes

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