5-Bromo-2-chloropyridine → HCID 86666292, compound

HRID 1026286Notes

Reaction equation

HRID 1026286 reaction equation
CON(C)[C:4](=[O:16])[CH2:5][CH:6]([NH:8][C:9](=[O:15])[O:10][C:11]([CH3:14])([CH3:13])[CH3:12])[CH3:7].Br[C:19]1[CH:20]=[CH:21][C:22]([Cl:25])=[N:23][CH:24]=1>>[Cl:25][C:22]1[N:23]=[CH:24][C:19]([C:4](=[O:16])[CH2:5][CH:6]([NH:8][C:9](=[O:15])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH3:7])=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 27344145-Bromo-2-chloropyridineHCID 74393680HCID 74393680, compound

Product 1

HCID 86666292HCID 86666292, compound

Procedure

Using tert-butyl {3-[methoxy(methyl)amino]-1-methyl-3-oxopropyl}carbamate and 5-bromo-2-chloropyridine, and in the same manner as in Example 24, step E, the title compound was obtained.

Sources & evidence

ORD record
ord-9f1140e0e2c54e0493988e97d597fe0a
Source dataset
uspto-grants-2014_05
Patent number
US08729102B2

Reaction notes

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