Tetrabutylammonium Fluoride → HCID 67777325, compound

Participants

Reaction Steps

A mixture of 2-(6-(methoxymethoxy)-2-methyl-2,3-dihydrobenzofuran-2-yl)-5-(triisopropylsilyloxy)pyridine (8 g) and tetrabutylammonium fluoride (5.66 g) in THF (30 mL) was stirred at ambient temperature for 30 min. The mixture was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane/methanol) to afford the title compound (4.66 g).

Provenance & Evidence