Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | HCID 58946729 | HCID 58946729 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 58946770 | HCID 58946770 | 60% |
Reaction Steps
To a solution of 112b (20g, 38.8 mmol) in toluene (100 ml) was added BnNH2 (12.48 g, 116.5 mmol). The reaction mixture was stirred at 90° C. for 3 h. Then the mixture was purified through a silica gel column eluting with PE:EA=50:1 to 10:1 to give 112c as a white crystal (10.7 g, 60%) MS: [M+H]+: 461
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08729072B2 |
|---|
| Source dataset | uspto-grants-2014_05 |
|---|
| ORD ID | ord-34777b66434c40929aedeae6c5c1731b |
|---|
| Source note | uspto-grants-2014_05 |
|---|
