8-Cyclohexyl-2-methanesulfonyl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester → 8-Cyclohexyl-2-[4-(2-isopropylsulfamoyl-ethyl)-phenylamino]-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester
Reaction equation
[CH2:17]([CH3:18])[O:19][C:20](=[O:21])[c:22]1[c:23](=[O:42])[c:24]2[c:25]([n:26][c:27]([S:30]([CH3:31])(=[O:32])=[O:33])[n:28][cH:29]2)[n:34]([CH:36]2[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41]2)[cH:35]1.[CH:1]([CH3:2])([CH3:3])[NH:4][S:5](=[O:6])(=[O:7])[CH2:8][CH2:9][c:10]1[cH:11][cH:12][c:13]([NH2:16])[cH:14][cH:15]1>>[CH:1]([CH3:2])([CH3:3])[NH:4][S:5](=[O:6])(=[O:7])[CH2:8][CH2:9][c:10]1[cH:11][cH:12][c:13]([NH:16][c:27]2[n:26][c:25]3[c:24]([c:23](=[O:42])[c:22]([C:20]([O:19][CH2:17][CH3:18])=[O:21])[cH:35][n:34]3[CH:36]3[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41]3)[cH:29][n:28]2)[cH:14][cH:15]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-68e4cf58985643b3ab897ce73c995f2d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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