HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86683725, compound → HCID 86683726, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86683725 | HCID 86683725 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 86683726 | HCID 86683726 | 96.7% |
Reaction Steps
To a solution of 112i (800 mg, 3.0 mmol) in THF (80 ml) was added Pd/C (50 mg) in MeOH (20 ml) at room temperature. The reaction mixture was hydrogenated at atmospheric hydrogen pressure and stirred at room temperature overnight. The mixture was filtered and the filtrate was evaporated to give 112j as a colorless oil (680 mg, 90%).MS: [M+H]+: 235
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729072B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-4ed7e8a42e6e4aeaad689609c4b28522 |
| Source note | uspto-grants-2014_05 |