HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 67106526, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 5-Indolylboronic acid | HCID 2734361 | — |
| Reactant | HCID 178499122 | HCID 178499122 | — |
| Catalyst | Cupric acetate | HCID 8895 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 67106526 | HCID 67106526 | 24.5% |
Reaction Steps
1H-1,2,4-triazole-3-carboxylic acid methyl ester (1.12 g, 8.79 mmol), 1H-indol-5-ylboronic acid (1.42 g, 8.79 mmol), N,N-dimethylformamide (90 mL), copper (II) acetate (1.20 g, 6.60 mmol) and pyridine (1.40 mL, 17.3 mmol) were reacted according to the same procedure as Preparation 1 to give the title compound (519.7 mg, 2.15 mmol, 24% Yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729273B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-2a386170bbe04cd385fdda006dc6854c |
| Source note | uspto-grants-2014_05 |