(Z)-Prop-1-en-1-ylboronic acid → HCID 70664442, compound

HRID 1026654Notes

Reaction equation

HRID 1026654 reaction equation
C([N:8]1[CH2:16][C@@H:15]2[C@:10]([CH3:24])([CH2:11][CH2:12][C:13]3[C:20]([Cl:21])=[C:19]([CH2:22][CH3:23])[CH:18]=[CH:17][C:14]=32)[CH2:9]1)C1C=CC=CC=1.C(/B(O)O)=C/C>>[ClH:21].[Cl:21][C:20]1[C:13]2[CH2:12][CH2:11][C@@:10]3([CH3:24])[C@@H:15]([CH2:16][NH:8][CH2:9]3)[C:14]=2[CH:17]=[CH:18][C:19]=1[CH2:22][CH3:23]

Participants

3

Reactant 2

HCID 5355539(Z)-Prop-1-en-1-ylboronic acidHCID 70664607HCID 70664607, compound

Product 1

HCID 70664442HCID 70664442, compound

Procedure

Similar protocols to procedures in example 5-7 (using trans-2-benzyl-6-chloro-7-ethyl-3a-methyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]isoindole and (Z)-prop-1-enylboronic acid) were employed to afford trans-6-chloro-7-ethyl-3a-methyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]isoindole hydrochloride, m/z=264.2 [M+H]+.

Sources & evidence

ORD record
ord-0fb3a9bf6d734e49ae43447310f4589e
Source dataset
uspto-grants-2014_05
Patent number
US08729274B2

Reaction notes

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