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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1026655Generated: November 2, 2026

Tetrahydrofuran → HCID 24885422, compound

https://huagongshe.com/reaction/1026655

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantDiethyl (cyanomethyl)phosphonateHCID 75676—
ReactantLithium BromideHCID 82050—
ReactantHCID 68694918HCID 68694918—
ProductHCID 24885422HCID 24885422—

Reaction Steps

The mixture of triethylamine (13.8 mmol), lithium bromide (8.2 mmol) and diethylcyanomethylphosphonate (7.2 mmol) in 25 ml tetrahydrofuran was stirred for 20 minutes at room temperature. To the suspension, (5)-{3-[4-(4-oxo-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide (6.9 mmol) was added. The reaction mixture stirred for 5 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729269B2
Source datasetuspto-grants-2014_05
ORD IDord-59478aa3355940bf87722f7da2bed9c8
Source noteuspto-grants-2014_05