(Diethylamino)sulfur trifluoride → HCID 11463639, compound

Participants

Reaction Steps

The title compound was prepared by reacting ((S)—N-{3-[4-(4-hydroxy-4-methoxymethyl piperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide (1.37 mmol) with DAST (4.10 mmol) in dichloromethane (10 ml) at a temperature 0° C. for one hour and by purifying the compound by silica gel column chromatography in 68% yield.

Provenance & Evidence