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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1026682Generated: October 31, 2026

Sodium Methoxide → HCID 11246439, compound

https://huagongshe.com/reaction/1026682

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium MethoxideHCID 10942334—
ReactantHCID 11382912HCID 11382912—
SolventMethanolHCID 887—
ProductHCID 11246439HCID 1124643982%

Reaction Steps

The title compound was prepared by reacting (S)—N-{3-[4-(1-oxa-6-aza-spiro[2.5]oct-6-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide (1.3 mmol) with sodium methoxide (1.6 mmol) in methanol (10 ml) at a temperature 65° C. for 6 hours and by purifying the compound by silica gel column chromatography in 82% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729269B2
Source datasetuspto-grants-2014_05
ORD IDord-4b04325ee1a941e1904994d0860516cb
Source noteuspto-grants-2014_05