HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → HCID 11246439, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 11382912 | HCID 11382912 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 11246439 | HCID 11246439 | 82% |
Reaction Steps
The title compound was prepared by reacting (S)—N-{3-[4-(1-oxa-6-aza-spiro[2.5]oct-6-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide (1.3 mmol) with sodium methoxide (1.6 mmol) in methanol (10 ml) at a temperature 65° C. for 6 hours and by purifying the compound by silica gel column chromatography in 82% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729269B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-4b04325ee1a941e1904994d0860516cb |
| Source note | uspto-grants-2014_05 |