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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1026707Generated: November 1, 2026

Sulfoxonium, trimethyl-, iodide (1:1) → HCID 11474864, compound

https://huagongshe.com/reaction/1026707

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSulfoxonium, trimethyl-, iodide (1:1)HCID 74498—
ReactantPotassium tert-butoxideHCID 23665647—
ReactantHCID 86599014HCID 86599014—
SolventDimethyl SulfoxideHCID 679—
ProductHCID 11474864HCID 1147486452%

Reaction Steps

The title compound was prepared by reacting (S)—N-[3-{4-[4-dicyanomethylidene piperidin-1-yl]-phenyl}-2-oxo-1,3-oxazolidin-5-ylmethyl]-acetamide (1.0 mmol, Example D), trimethyloxosulphonium iodide (1.3 mmol), potassium tert-butoxide (1.3 mmol) in dimethylsulfoxide (10 ml) at a temperature 25° C. for 14 hours in 52% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729269B2
Source datasetuspto-grants-2014_05
ORD IDord-79223a33f72649229699b0b8cefdabee
Source noteuspto-grants-2014_05