HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfoxonium, trimethyl-, iodide (1:1) → HCID 11475407, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfoxonium, trimethyl-, iodide (1:1) | HCID 74498 | — |
| Reactant | HCID 10340744 | HCID 10340744 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 11475407 | HCID 11475407 | 57% |
Reaction Steps
The title compound was prepared by reacting (S)—N-[3-{4-[4-dicyanomethylidene piperidin-1-yl]-3-fluorophenyl}-2-oxo-1,3-oxazolidin-5-ylmethyl]-acetamide (1.0 mmol, Example C), trimethyloxosulphonium iodide (1.3 mmol), potassium tert-butoxide (1.3 mmol) in dimethylsulfoxide (10 ml) at a temperature 25° C. for 14 hours in 57% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729269B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-76248113cee74559838be068040d2976 |
| Source note | uspto-grants-2014_05 |