HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropylamine → HCID 11452894, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | HCID 11382912 | HCID 11382912 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 11452894 | HCID 11452894 | 73% |
Reaction Steps
The title compound was prepared by reacting (S)—N-{3-[4-(1-oxa-6-aza-spiro[2.5]oct-6-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide (1.37 mmol) with cyclopropylamine (2.06 mmol) in methanol (10 ml) at a temperature 25° C. for 14 hours and by purifying the compound by silica gel column chromatography in 73% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729269B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-96e1107b477b4a6fa0a630e7141d7f79 |
| Source note | uspto-grants-2014_05 |