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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1026729Generated: November 1, 2026

Cyclopropylamine → HCID 11452894, compound

https://huagongshe.com/reaction/1026729

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropylamineHCID 69828—
ReactantHCID 11382912HCID 11382912—
SolventMethanolHCID 887—
ProductHCID 11452894HCID 1145289473%

Reaction Steps

The title compound was prepared by reacting (S)—N-{3-[4-(1-oxa-6-aza-spiro[2.5]oct-6-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide (1.37 mmol) with cyclopropylamine (2.06 mmol) in methanol (10 ml) at a temperature 25° C. for 14 hours and by purifying the compound by silica gel column chromatography in 73% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729269B2
Source datasetuspto-grants-2014_05
ORD IDord-96e1107b477b4a6fa0a630e7141d7f79
Source noteuspto-grants-2014_05