反应详情

Under the protection of nitrogen gas, the 2,2′,6,6′-tetranitrobiphenyl (1.00 g, 3 mmol) and 100 mg 10% Pd/C were added into a 100 mL hydrogenation flask. Subsequently, 20 mL of methanol is added, and the resultant mixture was bubbled with nitrogen gas. The hydrogenation flask was placed in an autoclave, and was added 10 atm of hydrogen gas. After 6 hours, the reaction is completed. The resultant was filtered to remove Pd/C, and was rotary evaporated to remove the methanol. The residue was extracted with ethyl acetate and water, dried over anhydrous sodium sulfate, filtered, and votary evaporated, to afford the product in a yield of 88%.

1. customthe resultant mixture was bubbled with nitrogen gas
2. additionwas added 10 atm of hydrogen gas
3. filtrationThe resultant was filtered
4. customto remove Pd/C
5. customwas rotary evaporated
6. customto remove the methanol
7. extractionThe residue was extracted with ethyl acetate and water
8. dry with materialdried over anhydrous sodium sulfate
9. filtrationfiltered
10. customvotary evaporated, to afford the product in a yield of 88%