HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonamide → N-[7-(3-Fluorobenzylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonamide | HCID 72879 | — |
| Reactant | 7-(3-Fluorobenzylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid | HCID 67540477 | — |
| Product | N-[7-(3-Fluorobenzylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]methanesulfonamide | HCID 67540529 | — |
Reaction Steps
In the same manner as in Example 1, step 6 and using 7-(3-fluorobenzylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (0.09 g, 0.18 mmol) obtained in step 2 and methanesulfonamide (0.1 g, 1.08 mmol), compound a-6 (0.06 g, 64%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729264B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-167fed640e9f4f3b9c2697bd8ef9ae37 |
| Source note | uspto-grants-2014_05 |