4-(1H-pyrazol-1-yl)piperidine hydrochloride → 7-Benzylamino-3-ethoxycarbonyl-6-[4-(pyrimidin-5-yl)piperidine-1-carbonyl]pyrazolo[1,5-a]pyrimidine

Participants

Reaction Steps

In the same manner as in Example 21, step 5 and using 7-benzylamino-3-ethoxycarbonylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid (0.16 g, 0.47 mmol) obtained in Example 21, step 4 and 4-(pyrimidin-5-yl)piperidine (WO2004/094371, 0.09 g, 0.57 mmol), the title compound (0.20 g, 0.41 mmol) was obtained.

Provenance & Evidence