HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Chlorophenyl)piperidine → 7-Benzylamino-6-[4-(4-chlorophenyl)piperidine-1-carbonyl]-3-ethoxycarbonylpyrazolo[1,5-a]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Chlorophenyl)piperidine | HCID 1203613 | — |
| Reactant | 7-Benzylamino-3-ethoxycarbonylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid | HCID 67540794 | — |
| Product | 7-Benzylamino-6-[4-(4-chlorophenyl)piperidine-1-carbonyl]-3-ethoxycarbonylpyrazolo[1,5-a]pyrimidine | HCID 67540539 | 81% |
Reaction Steps
In the same manner as in Example 21, step 5 and using 7-benzylamino-3-ethoxycarbonylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid (0.20 g, 0.58 mmol) obtained in Example 21, step 4 and 4-(4-chlorophenyl)piperidine (0.14 g, 0.70 mmol), the title compound (0.24 g, 81%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729264B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-dce19a1850ed428f9deb1ba5fc78c44a |
| Source note | uspto-grants-2014_05 |