反应详情

In the same manner as in Example 1, step 2 and using 3-ethoxycarbonyl-7-hydroxypyrazolo[1,5-a]pyrimidine-6-carboxylic acid (583 mg, 2.32 mmol) obtained in Example 19, step 2 and 4-methyl-4-phenylpiperidine (Journal of Medicinal Chemistry, vol. 41, page 5320, 590 mg, 2.79 mmol), the title compound (650 mg, 69%) was obtained.