Ethanesulfonamide → HCID 67540572, compound

HRID 1026937Notes

Reaction equation

HRID 1026937 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH2:13][CH2:12][N:11]([C:14]([C:16]2[CH:17]=[N:18][C:19]3[N:20]([N:30]=[CH:31][C:32]=3[C:33]([OH:35])=O)[C:21]=2[NH:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=2[CH3:29])=[O:15])[CH2:10][CH2:9]1.[CH2:36]([S:38]([NH2:41])(=[O:40])=[O:39])[CH3:37]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH2:9][CH2:10][N:11]([C:14]([C:16]2[CH:17]=[N:18][C:19]3[N:20]([N:30]=[CH:31][C:32]=3[C:33]([NH:41][S:38]([CH2:36][CH3:37])(=[O:40])=[O:39])=[O:35])[C:21]=2[NH:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=2[CH3:29])=[O:15])[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 73702EthanesulfonamideHCID 67540834HCID 67540834, compound

Product 1

HCID 67540572HCID 67540572, compoundYield 19.2%

Procedure

In the same manner as in Example 1, step 6 and using 6-[4-(2-chlorophenyl)piperazine-1-carbonyl]-7-(2-methylphenylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (0.110 g, 0.224 mmol) obtained in step 2 and ethanesulfonamide (0.049 g, 0.448 mmol), the title compound (0.025 g, 19%) was obtained.

Sources & evidence

ORD record
ord-10b591a3d6b14a48a222ea9ede6c5bd3
Source dataset
uspto-grants-2014_05
Patent number
US08729264B2

Reaction notes

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