HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanesulfonamide → N-[7-(2-Methylphenylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]cyclopropanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanesulfonamide | HCID 15765418 | — |
| Reactant | 7-(2-Methylphenylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid | HCID 67540621 | — |
| Product | N-[7-(2-Methylphenylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]cyclopropanesulfonamide | HCID 67540653 | 63% |
Reaction Steps
In the same manner as in Example 1, step 6 and using 7-(2-methylphenylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (0.30 g, 0.66 mmol) obtained in Example 39, step 2 and cyclopropanesulfonamide (0.40 g, 3.3 mmol), the title compound (0.23 g, 63%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729264B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-5b226262194c4467a756d6ca0f3f88ff |
| Source note | uspto-grants-2014_05 |