Ethanesulfonamide → HCID 67541085, compound

HRID 1026943Notes

Reaction equation

HRID 1026943 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[N:14]3[N:15]=[CH:16][C:17]([C:18](O)=[O:19])=[C:13]3[N:12]=[CH:11][C:10]=2[C:21]([N:23]2[CH2:28][CH2:27][CH:26]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)[CH2:25][CH2:24]2)=[O:22])[CH:5]=[CH:6][CH:7]=1.[CH2:35]([S:37]([NH2:40])(=[O:39])=[O:38])[CH3:36]>>[CH3:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[N:14]3[N:15]=[CH:16][C:17]([C:18]([NH:40][S:37]([CH2:35][CH3:36])(=[O:39])=[O:38])=[O:19])=[C:13]3[N:12]=[CH:11][C:10]=2[C:21]([N:23]2[CH2:28][CH2:27][CH:26]([C:29]3[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=3)[CH2:25][CH2:24]2)=[O:22])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 73702EthanesulfonamideHCID 67540689HCID 67540689, compound

Product 1

HCID 67541085HCID 67541085, compoundYield 27.4%

Procedure

In the same manner as in Example 1, step 6 and using 7-(3-methylphenylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (0.061 g, 0.14 mmol) obtained in step 2 and ethanesulfonamide (0.073 g, 0.70 mmol), the title compound (0.021 g, 27%) was obtained.

Sources & evidence

ORD record
ord-ee15a9ff4e32421d88c85235a5560313
Source dataset
uspto-grants-2014_05
Patent number
US08729264B2

Reaction notes

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