HCID 67540800, compound → HCID 67540801, compound

Participants

Reaction Steps

N-[7-(2-Benzyloxyphenylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]ethanesulfonamide (120 mg, 0.19 mmol) obtained in Example 48, step 3 was dissolved in THF (5 mL), 10 wt % palladium-activated carbon (12 mg) was added, and the mixture was stirred at room temperature for 7 hr under a hydrogen atmosphere, and at 60° C. for 1 hr. The mixture was allowed to cool, and the reaction mixture was filtered. The obtained solvent was evaporated under reduced pressure to give the title compound (85 mg, 88%).

Provenance & Evidence