2,2,2-Trifluoroethane-1-sulfonamide → N-[7-(2-Methylphenylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]2,2,2-trifluoroethanesulfonamide

Participants

Reaction Steps

In the same manner as in Example 1, step 6 and using 7-(2-methylphenylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (0.12 g, 0.27 mmol) obtained in Example 39, step 2 and 2,2,2-trifluoroethanesulfonamide (WO1984/02650, 0.21 g, 1.33 mmol), the title compound (0.07 g, 43%) was obtained.

Provenance & Evidence