Ethanesulfonamide → HCID 67541391, compound

HRID 1026975Notes

Reaction equation

HRID 1026975 reaction equation
[CH3:1][C:2]1[C:7]([NH:8][C:9]2[N:14]3[N:15]=[CH:16][C:17]([C:18]([OH:20])=O)=[C:13]3[N:12]=[CH:11][C:10]=2[C:21]([N:23]2[CH2:28][CH2:27][CH:26]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)[CH2:25][CH2:24]2)=[O:22])=[CH:6][CH:5]=[CH:4][N:3]=1.[CH2:35]([S:37]([NH2:40])(=[O:39])=[O:38])[CH3:36]>>[CH3:1][C:2]1[C:7]([NH:8][C:9]2[N:14]3[N:15]=[CH:16][C:17]([C:18]([NH:40][S:37]([CH2:35][CH3:36])(=[O:39])=[O:38])=[O:20])=[C:13]3[N:12]=[CH:11][C:10]=2[C:21]([N:23]2[CH2:28][CH2:27][CH:26]([C:29]3[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=3)[CH2:25][CH2:24]2)=[O:22])=[CH:6][CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 73702EthanesulfonamideHCID 67540505HCID 67540505, compound

Product 1

HCID 67541391HCID 67541391, compoundYield 31.5%

Procedure

In the same manner as in Example 1, step 6 and using 7-(2-methyl-3-pyridylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (0.05 g, 0.11 mmol) obtained in step 2 and ethanesulfonamide (0.052 g, 0.55 mmol), the title compound (0.019 g, 31%) was obtained.

Sources & evidence

ORD record
ord-8c6987e7dc34472d97a8950f33521cef
Source dataset
uspto-grants-2014_05
Patent number
US08729264B2

Reaction notes

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