HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminoindole → 3-Ethoxycarbonyl-7-(4-indolylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminoindole | HCID 583431 | — |
| Reactant | 7-Chloro-3-ethoxycarbonyl-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine | HCID 86646290 | — |
| Product | 3-Ethoxycarbonyl-7-(4-indolylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine | HCID 67540792 | 98.3% |
Reaction Steps
In the same manner as in Example 19, step 5 and using 7-chloro-3-ethoxycarbonyl-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine (0.20 g, 0.48 mmol) obtained in Example 19, step 4 and 4-aminoindole (0.128 g, 0.97 mmol), the title compound (0.240 g, 98%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729264B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-ccf2ac18944f431c8a6df42f5cc8db49 |
| Source note | uspto-grants-2014_05 |