HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminoindole → 3-Ethoxycarbonyl-7-(5-indolylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminoindole | HCID 78867 | — |
| Reactant | 7-Chloro-3-ethoxycarbonyl-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine | HCID 86646290 | — |
| Product | 3-Ethoxycarbonyl-7-(5-indolylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine | HCID 67540795 | 100.5% |
Reaction Steps
In the same manner as in Example 19, step 5 and using 7-chloro-3-ethoxycarbonyl-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine (0.15 g, 0.36 mmol) obtained in Example 19, step 4 and 5-aminoindole (0.072 g, 0.54 mmol), the title compound (0.184 g, 99%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729264B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-1a4a0a7bd5214fd0891722e4493c3dfd |
| Source note | uspto-grants-2014_05 |