Ethanesulfonamide → HCID 67540620, compound

HRID 1027001Notes

Reaction equation

[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:13][CH2:12][N:11]([C:14]([C:16]3[CH:17]=[N:18][C:19]4[N:20]([N:30]=[CH:31][C:32]=4[C:33](O)=[O:34])[C:21]=3[NH:22][C:23]3[CH:28]=[CH:27][CH:26]=[C:25]([CH3:29])[CH:24]=3)=[O:15])[CH2:10][CH2:9]2)=[CH:4][CH:3]=1.[CH2:36]([S:38]([NH2:41])(=[O:40])=[O:39])[CH3:37]>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:13][CH2:12][N:11]([C:14]([C:16]3[CH:17]=[N:18][C:19]4[N:20]([N:30]=[CH:31][C:32]=4[C:33]([NH:41][S:38]([CH2:36][CH3:37])(=[O:40])=[O:39])=[O:34])[C:21]=3[NH:22][C:23]3[CH:28]=[CH:27][CH:26]=[C:25]([CH3:29])[CH:24]=3)=[O:15])[CH2:10][CH2:9]2)=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 73702Ethanesulfonamide

HCID 67539685HCID 67539685, compound

Product 1

HCID 67540620HCID 67540620, compoundYield 37%

Procedure

In the same manner as in Example 1, step 6 and using 6-[4-(4-fluorophenyl)piperidine-1-carbonyl]-7-(3-methylphenylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (0.05 g, 0.11 mmol) obtained in step 2 and ethanesulfonamide (0.070 g, 0.64 mmol), the title compound (0.022 g, 37%) was obtained.

Sources & evidence

ORD record: ord-d5b1da86669c45a686ae3a5368527172
Source dataset: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08729264B2

Reaction notes

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