反应详情

In the same manner as in Example 21, step 5 and using 3-ethoxycarbonyl-7-(2-fluoro-5-methylphenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid (160 mg, 0.46 mmol) obtained in Example 90, step 2 and 4-(2,4-difluorophenyl)piperidine hydrochloride (WO2007/018998, 160 mg, 0.69 mmol), the title compound (117 mg, 47%) was obtained.