Ethanesulfonamide → HCID 67540562, compound

Participants

Reaction Steps

In the same manner as in Example 1, step 6 and using 7-(2-methylphenylamino)-6-(spiro[indane-1,4′-piperidine]-1′-ylcarbonyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (0.06 g, 0.13 mmol) obtained in step 4 and ethanesulfonamide (0.066 g, 0.62 mmol), the title compound (0.073 g, 100%) was obtained. ESI-MS m/z: 573 (M+H)+; 1H-NMR (CDCl3,δ):1.46 (t, J=7.3 Hz, 3H), 1.46-1.53 (m, 2H), 1.57-1.70 (m, 2H), 1.98 (t, J=7.3 Hz, 2H), 2.43 (s, 3H), 2.92 (t, J=7.1 Hz, 2H), 3.61 (q, J=7.5 Hz, 2H), 3.70-4.06 (m, 4H), 7.09-7.23 (m, 4H), 7.29-7.42 (m, 4H), 8.35 (s, 1H), 8.35 (s, 1H), 8.63 (s, 1H), 10.54 (s, 1H).

Provenance & Evidence