Diisopropyl Ether → HCID 67541275, compound

Participants

Reaction Steps

N-[7-Benzylamino-6-(3-methylspiro[inden-1,4′-piperidine]-1′-ylcarbonyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]methanesulfonamide (0.035 g, 0.061 mmol) obtained in Example 111, step 3 was dissolved in ethanol (2.0 ml), 10% palladium-carbon (0.079 g, 0.382 mmol) was added, and the mixture was stirred at room temperature for 4 hr. The reaction mixture was filtered through celite and washed with chloroform, and the filtrate was concentrated under reduced pressure to give a residue. Diisopropyl ether was added to the residue and the precipitated crystals were collected by filtration to give the title compound (0.011 g, 32%).

Provenance & Evidence