HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86710674, compound → HCID 178492917, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86710674 | HCID 86710674 | — |
| Reactant | HCID 178418934 | HCID 178418934 | — |
| Product | HCID 178492917 | HCID 178492917 | 100.1% |
Reaction Steps
Following standard GENERAL METHOD 1-4 for Suzuki coupling using (2-fluoro-4-methoxy-5-(6-(methyl(2,2,6,6-tetramethylpiperidin-4-yl)amino)pyridazin-3-yl)phenyl)boronic acid (50 mg, 0.12 mmol) and 4-bromo-1H-imidazole (35.3 mg, 0.24 mmol) afforded 6-(4-fluoro-5-(1H-imidazol-4-yl)-2-methoxyphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine (52.7 mg) MS [M+H+]=439.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729263B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-1414d0798e93421789941b55e45dd9d3 |
| Source note | uspto-grants-2014_05 |