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HRID1027277

反应详情

EQUATION

反应方程式

HRID 1027277 的结构方程式

REACTANTS

反应物

2
结构：COc1cc(O[Si](C)(C)C(C)(C)C)ccc1B1OC(C)(C)C(C)(C)O1
HCID86710628

未命名化合物

结构：CC1(C)CC(Cc2ccc(Cl)nn2)CC(C)(C)N1
HCID86710692

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(O)ccc1-c1ccc(CC2CC(C)(C)NC(C)(C)C2)nn1
HCID136377169

未命名化合物

收率 61.9%

PROCEDURE

实验过程

Following standard GENERAL METHOD 1-4 for Suzuki coupling using tert-butyl(3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)dimethylsilane (408 mg, 1.12 mmol) and 3-chloro-6-((2,2,6,6-tetramethylpiperidin-4-yl)methyl)pyridazine (200 mg, 0.75 mmol) affords 3-methoxy-4-(6-((2,2,6,6-tetramethylpiperidin-4-yl)methyl)pyridazin-3-yl)phenol (165 mg) MS [M+H+]=356.1.