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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1027440Generated: October 30, 2026

4-Fluorobenzoyl chloride → 4-Fluoro-N-{4-[(S)-3-((S)-2-methyl-pyrrolidin-1-yl)-cyclopentyl]-phenyl}-benzamide

https://huagongshe.com/reaction/1027440

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzoyl chlorideHCID 67879—
Reactant4-[(S)-3-((S)-2-Methyl-pyrrolidin-1-yl)-cyclopentyl]-phenylamineHCID 67479147—
Product4-Fluoro-N-{4-[(S)-3-((S)-2-methyl-pyrrolidin-1-yl)-cyclopentyl]-phenyl}-benzamideHCID 67479109—

Reaction Steps

The title compound was synthesized essentially in the same manner as Example 28 by employing 4-[(S)-3-((S)-2-methyl-pyrrolidin-1-yl)-cyclopentyl]-phenylamine (Intermediate 14) and 4-fluorobenzoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08735385B2
Source datasetuspto-grants-2014_05
ORD IDord-626a6a4efe544a12ab549db432fbdfc4
Source noteuspto-grants-2014_05