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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1027441Generated: October 27, 2026

4-Chlorobenzoyl chloride → 4-Chloro-N-{4-[(S)-3-((S)-2-methyl-pyrrolidin-1-yl)-cyclopentyl]-phenyl}-benzamide

https://huagongshe.com/reaction/1027441

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorobenzoyl chlorideHCID 8501—
Reactant4-[(S)-3-((S)-2-Methyl-pyrrolidin-1-yl)-cyclopentyl]-phenylamineHCID 67479147—
Product4-Chloro-N-{4-[(S)-3-((S)-2-methyl-pyrrolidin-1-yl)-cyclopentyl]-phenyl}-benzamideHCID 67479029—

Reaction Steps

The title compound was synthesized essentially in the same manner as Example 28 by employing 4-[(S)-3-((S)-2-methyl-pyrrolidin-1-yl)-cyclopentyl]-phenylamine (Intermediate 14) and 4-chlorobenzoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08735385B2
Source datasetuspto-grants-2014_05
ORD IDord-8ec49410b1244f7d819c1867c4b66dde
Source noteuspto-grants-2014_05